Immunology Research Scientist

1 month ago

Shanghai, Shanghai, China Roche Full time

Job Summary

We are seeking a highly skilled Immunology Research Scientist to join our team at Roche. The successful candidate will collaborate with a group of immunology scientists and associates to provide expert biology support to preclinical and clinical studies for the discovery and development of new therapeutic agents.

Key Responsibilities

  • Contribute to new medical hypothesis, new target validation, new project initiation and progression, and drafting and execution of research plans for nominating new projects.
  • Apply skills in drug discovery to assess the potency, selectivity, safety, PK and PD of novel molecules.
  • Drive or support target identifications in collaboration with translational medicine, disease biology research, and chemistry teams.
  • Initiate new drug discovery projects based on scientific insight with cross-functional input.
  • Design and implement various in vitro and in vivo studies to study potency, selectivity, and to elucidate molecular mechanism of drug action and efficacy.
  • Perform scientific analysis for results interpretation and present them collaboratively.
  • Investigate and develop methods or technologies for the rapid advancement of projects.
  • Prepare standard operational protocols, study reports and high-quality manuscripts.

Requirements

  • PhD in Immunology, Nephrology, Rheumatology or a related field.
  • Post-doctoral training experience is preferred.
  • Industrial experience in drug discovery is a plus.
  • Strong background in immunology and experience with autoimmune diseases or kidney diseases preferred.

Leadership Competencies

  • Effective communication and collaboration skills.
  • Ability to train junior level associates and/or scientists.

Job Required Competencies

  • Deep knowledge of immunology.
  • Disease biology of the gut, kidneys and connective tissues is preferred.
  • Proficient in designing and conducting experiments involving state-of-the-art techniques within the areas of immunology, biochemistry, molecular biology, and pharmacology.
  • Ability to understand chemistry and DMPK results and collaborate effectively cross-functions.
  • Recognition of novelty of patentable ideas where applicable and contribution to patents.
  • Contribution to scientific publications.
  • Good communication in English and ability to present results both inside and outside of company.

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