临床前体内药理研究员(019038)

工作职责
Responsibility:
1、WorkingcloselywithMedicinal Chemistry/BiologicsDiscovery/in vitroPharmacology
teamsdevelopingin vivomodels to test the activity oftest articlesand perform in-depth
characterization of mechanismstudiesin these models;
2、Collaborate with the broader scientific teams to design and executein vivoPoC
experiments aimingat defining the mechanism(s) of actionof test articles;
3、Perform in-depth literature search, design/executeimmunologyin vivomodels
exploring the PD of test articles supporting differentiationpointsidentification/
indication expansion;
4、Serve asrepresentative of immunologyin vivoteam inthe project teamresponsible for
addressingtechniqueissues/giving suggestions to supportachievingkeymilestones;
5、Responsible for experiment tissue collection/biomarkerassessment/data
analysis/experiment report drafting/IND submission material drafting;
6、Support new target evaluation, MoA analysisand proposal preparation.

任职要求
1、Masteror PhDdegree in the field of immunology, immuno-oncology, pharmacology or
veterinarymedicine with at least three years(for PhD level candidates)or six years(for
Master level candidates)of workingexperience inindustrysettings (TopCROs/Pharma/Bio-Pharma/Biotech).
2、Strong publication/patent track records are preferred.
3、Experience inindependentlyleadingimmunology&inflammationin vivoprojectsto
PCC/IND milestones are highly preferred.
4、Hands-on experienceand in-depthknowledgeininvivoanimal models of
inflammatory/autoimmune diseases orImmuno-oncology,proficient in routine animal
experiment/handlingskills.
5、Hands-on experienceand in-depthknowledgeinexvivoimmunology/molecular
assays/techniquesincludingflow cytometry, ELISA,MSD, Luminex,CBA,western blot,
IHC/IF, qPCRetc.
6、Experience in sequencing(DNA/RNA)orproteomicsdataanalysisor
mathematic/computational modeling is a plus.
7、Strong ability in literature/patent search,analytical thinking and problemsolving.
8、Goodverbal/reading/writingskillsin Englishas proved by CET6/IELTS/TOEFL/GRE scores.
9、Excellentanalytical, organizationaland communications skillswithdemonstratedability
to work collaboratively with peers across multiplefunctions.

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